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T. C. McDevitt
Models
Published Models
Cell Culture
Human iPSC Wildtype Colony Growth
Morpheus Model ID:
M7671
Introduction Human induced pluripotent stem cells (hiPSCs) can be grown in cell culture where they self-organize spatial patterns. Libby et al. have employed inducible CRISPR interference-driven genetic perturbations to modulate mechanical cell properties like cell-cell adhesion and cortical tension.
A. R. G. Libby
,
D. Briers
,
I. Haghighi
,
D. A. Joy
,
B. R. Conklin
,
C. Belta
,
T. C. McDevitt
(Authors)
L. Brusch
(Contributor)
DOI:10.1016/j.cels.2019.10.008
Models
Published Models
Cell Culture
Human iPSC ROCK1-KD : Wildtype Colony Patterning
Morpheus Model ID:
M7673
Introduction Human induced pluripotent stem cells (hiPSCs) can be grown in cell culture where they self-organize spatial patterns. Libby et al. have employed inducible CRISPR interference-driven genetic perturbations to modulate mechanical cell properties like cell-cell adhesion and cortical tension.
A. R. G. Libby
,
D. Briers
,
I. Haghighi
,
D. A. Joy
,
B. R. Conklin
,
C. Belta
,
T. C. McDevitt
(Authors)
L. Brusch
(Contributor)
DOI:10.1016/j.cels.2019.10.008
Models
Published Models
Cell Culture
Human iPSC CDH1-KD : Wildtype Colony Patterning
Morpheus Model ID:
M7672
Introduction Human induced pluripotent stem cells (hiPSCs) can be grown in cell culture where they self-organize spatial patterns. Libby et al. have employed inducible CRISPR interference-driven genetic perturbations to modulate mechanical cell properties like cell-cell adhesion and cortical tension.
A. R. G. Libby
,
D. Briers
,
I. Haghighi
,
D. A. Joy
,
B. R. Conklin
,
C. Belta
,
T. C. McDevitt
(Authors)
L. Brusch
(Contributor)
DOI:10.1016/j.cels.2019.10.008
Selected Publications
Perspective: The promise of multi-cellular engineered living systems
Recent technological breakthroughs in our ability to derive and differentiate induced pluripotent stem cells, organoid biology, …
R. D. Kamm
,
R. Bashir
,
N. Arora
,
R. D. Dar
,
M. U. Gillette
,
L. G. Griffith
,
M. L. Kemp
,
K. Kinlaw
,
M. Levin
,
A. C. Martin
,
T. C. McDevitt
,
R. M. Nerem
,
M. J. Powers
,
T. A. Saif
,
J. Sharpe
,
S. Takayama
,
S. Takeuchi
,
R. Weiss
,
K. Ye
,
H. G. Yevick
,
M. H. Zaman
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