CellType

Let’s go through an example. We’ll construct a model in which an intracellular cell cycle network (ODE) regulates the division of motile cells which (CPM) release a diffusive cytokine (PDE) which, in turn, controls the cell cycle (ODE).

Introduction This model shows the original cellular Potts model (a.k.a. Glazier-Graner model) of cell sorting based on the Steinberg’s differential adhesion hypothesis. Yellow cells engulf the red cells as a result of differential adhesion.

This model also requires the separate file boundary.tiff. Introduction The immune system plays an important role in controlling infections and tumors. Knowledge about the mechanisms through which the immune system accomplishes this can be exploited to develop immunotherapies.

Multiple models in epithelial-mesenchymal transitions (EMT) Introduction We model epithelial-mesenchymal transition (EMT) by first assembling an ODE model for intracellular Yes-associated protein (YAP) signalling and then embedding this single cell model within individual cells in a multiscale simulation.