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‘On macOS, how do I install Morpheus?’

Derived from the seminal Hodgkin-Huxley and FitzHugh-Nagumo models, the Barkley model is probably the simplest continuous model for excitable media. It replaces the cubic term in the FitzHugh-Nagumo model with a piece-wise linear term as a simplification that enables fast simulation.

Examples Menu To explore the potential and modeling features, it is the best to learn by example. Morpheus comes with a range of fully functional example models showcasing a number of model formalism and modeling features.

To show SBML support in Morpheus as of version 2.1 in practice, we give a step-by-step example of how to download, import and extend an SBML model. 1. Get an SBML Model from BioModels First, we browse the BioModels model repository and select a model.

Now we finally arrive at the 3D model. As an example, we further develop the coupled PDE and CPM model with mechanical interaction. Similar to the 1D to 2D case, it is straighforward to extend the dimensionality to 3D.

Introduction This example model cell fate decisions during early patterning of the pancreas (de Back et al., 2012). The simple gene regulatory network of each cell is coupled to adjacent cells by lateral (juxtacrine) signaling.

ODE model of the Xenopus oocyte cell cycle coupled to 2D shaped CPM cells that perform divide based on component concentrations Introduction This multiscale model example shows how to define a coupled system of continuous ODEs in discrete CPM cells, how to specify and change time scales between these model formalisms.

Spatial distribution of GTPase activity Introduction The actin cytoskeleton is regulated by a set of proteins called Small GTPases. The spatial distribution of GTPase activity changes on a timescale of seconds in rapidly moving cells like white blood cells (neutrophils).

This is the seventh bug fix release of the 2.3 series.

New GUI functionalities, better performance with OpenMP parallelization of Mappers and Reporters, improved online courses and much more