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Partial Differential Equation
Models
Contributed Examples
PDE
FitzHugh–Nagumo Waves
Morpheus Model ID:
M2014
Waves produced by an excitable FitzHugh–Nagumo PDE. Introduction We will here take a closer look at waves produced by an excitable FitzHugh–Nagumo PDE in a periodic 1D domain, in a periodic 2D domain.
L. Edelstein-Keshet
(Author)
Y. Xiao
(Contributor)
L. Edelstein-Keshet: Mathematical Models in Cell Biology
Models
Contributed Examples
PDE
Diffusion
Morpheus Model ID:
M2017
Simulations of a diffusing field Introduction Here, we build up a simulation of diffusion over three successive files by: Starting with 1D and a short time scale in Diffusion1a_main.
L. Edelstein-Keshet
(Author)
Y. Xiao
(Contributor)
L. Edelstein-Keshet: Mathematical Models in Cell Biology
Models
Contributed Examples
PDE
Actin Waves
Morpheus Model ID:
M2013
Spatial relaxation oscillator produces spatial dynamics and spiral waves Introduction We consider a full spatial variant of the Morpheus Model ID: M2012"model of a F-actin negative feedback to GTPase system.
L. Edelstein-Keshet
(Author)
Y. Xiao
(Contributor)
L. Edelstein-Keshet: Mathematical Models in Cell Biology
Models
Contributed Examples
Multiscale
Mass-conserving secretion and uptake of a diffusible signal
Morpheus Model ID:
M5491
Introduction The mass-conserving secretion and uptake of (signaling) molecules by cells can in Morpheus be achieved with Mappers and scaling fluxes by cell.volume. The intracellular amount of signal may trigger a change in a state variable that could downstream change cell behaviors.
L. Brusch
(Contributor)
Models
Published Models
Mouse
Liver Regeneration from CCl4
Morpheus Model ID:
M9147
Hepatocyte–sinusoid alignment (HSA) supports the coordination of hepatocytes during liver regeneration after damage by carbon tetrachloride. Introduction The regenerative capacity of the mammalian liver did already inspire the fate of Prometheus in Greek Myth but it still poses many questions today that call for spatio-temporal multicellular modeling.
S. Höhme
,
M. Brulport
,
A. Bauer
,
E. Bedawy
,
W. Schormann
,
M. Hermes
,
V. Puppe
,
R. Gebhardt
,
S. Zellmer
,
M. Schwarz
,
E. Bockamp
,
T. Timmel
,
J. G. Hengstler
,
D. Drasdo
(Authors)
D. Jahn
,
L. Brusch
(Contributors)
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