Time-Step

‘What is the difference between an Equation, a Rule and a Function ?’

At this point, you may be asking yourself: ‘All nice and well, but how can I control the relative time scales between the various models?’ And I’d respond:

ODE model of the Xenopus oocyte cell cycle coupled to 2D shaped CPM cells that perform divide based on component concentrations Introduction This multiscale model example shows how to define a coupled system of continuous ODEs in discrete CPM cells, how to specify and change time scales between these model formalisms.

The migration of zebrafish polster cells is oriented by the migration of follower cells, allowing robust long-range coordination of different cell populations. Introduction Collective cell migration is an important process during biological development and tissue repair.

Spatio-temporal model of planar polarity regulation during planarian regeneration Introduction This simulation reproduces Figure 4D of the referenced paper. Parameter values correspond to the β-catenin-1(RNAi) pattern as given in Table S2 of the referenced paper.

This model also requires the separate file boundary.tiff. Introduction The immune system plays an important role in controlling infections and tumors. Knowledge about the mechanisms through which the immune system accomplishes this can be exploited to develop immunotherapies.

Time sequence showing the changing shape of a CPM cell Introduction Not all cell shapes are circular. In this example, a single cell undergoes a whole series of deformations resulting in the development of irregular cell shapes.