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Tissue Engineering
Models
Published Models
Cell Culture
Human iPSC Wildtype Colony Growth
Morpheus Model ID:
M7671
Introduction Human induced pluripotent stem cells (hiPSCs) can be grown in cell culture where they self-organize spatial patterns. Libby et al. have employed inducible CRISPR interference-driven genetic perturbations to modulate mechanical cell properties like cell-cell adhesion and cortical tension.
A. R. G. Libby
,
D. Briers
,
I. Haghighi
,
D. A. Joy
,
B. R. Conklin
,
C. Belta
,
T. C. McDevitt
(Authors)
L. Brusch
(Contributor)
DOI:10.1016/j.cels.2019.10.008
Models
Published Models
Cell Culture
Human iPSC ROCK1-KD : Wildtype Colony Patterning
Morpheus Model ID:
M7673
Introduction Human induced pluripotent stem cells (hiPSCs) can be grown in cell culture where they self-organize spatial patterns. Libby et al. have employed inducible CRISPR interference-driven genetic perturbations to modulate mechanical cell properties like cell-cell adhesion and cortical tension.
A. R. G. Libby
,
D. Briers
,
I. Haghighi
,
D. A. Joy
,
B. R. Conklin
,
C. Belta
,
T. C. McDevitt
(Authors)
L. Brusch
(Contributor)
DOI:10.1016/j.cels.2019.10.008
Models
Published Models
Cell Culture
Human iPSC CDH1-KD : Wildtype Colony Patterning
Morpheus Model ID:
M7672
Introduction Human induced pluripotent stem cells (hiPSCs) can be grown in cell culture where they self-organize spatial patterns. Libby et al. have employed inducible CRISPR interference-driven genetic perturbations to modulate mechanical cell properties like cell-cell adhesion and cortical tension.
A. R. G. Libby
,
D. Briers
,
I. Haghighi
,
D. A. Joy
,
B. R. Conklin
,
C. Belta
,
T. C. McDevitt
(Authors)
L. Brusch
(Contributor)
DOI:10.1016/j.cels.2019.10.008
Models
Published Models
Cell Culture
Human ESC Colony Patterning
Morpheus Model ID:
M7675
Introduction The formation and maintenance of three germ layers in colonies of human embryonic stem cells (ESCs) is sensitive to the geometry of the colony. In vitro experiments with micropatterns controlling colony shape have previously addressed the underlying spatio-temporal patterning in Warmflash et al.
H. Fooladi
,
P. Moradi
,
A. Sharifi-Zarchi and B. Hosein Khalaj
(Authors)
H. Fooladi
,
L. Brusch
(Contributors)
DOI:10.1093/bioinformatics/btz201
Morpheus at Recent & Upcoming Events
Human Cell Atlas Developmental and Pediatric Cell Atlas Meeting
This meeting will bring together the Developmental and Pediatric Cell Atlas community of scientists, computational biologists, …
Sun, 20 Nov 2022 — Tue, 22 Nov 2022
Sorbonne Université, Centre International de Conférences
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