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Tumor
Models
Published Models
Human
Spatial Effects on Killing Kinetics of Cytotoxic T Lymphocytes
Morpheus Model ID:
M9495
This model also requires the separate file boundary.tiff. Introduction The immune system plays an important role in controlling infections and tumors. Knowledge about the mechanisms through which the immune system accomplishes this can be exploited to develop immunotherapies.
R. J. Beck
,
D. I. Bijker
,
J. B. Beltman
(Authors)
J. B. Beltman
,
D. Jahn
(Contributors)
DOI:10.1371/journal.pcbi.1007972
Models
Published Models
Cell Culture
Tumor Growth: Unlimited Oxygen and Glucose Supply
Morpheus Model ID:
M0007
Introduction In Jagiella et al. 2017 a quantitative single cell-based mathematical model for multi-cellular tumor spheroids was parametrized by Bayesian inference for different scenarios of nutrition and oxygen supply. The simulations generate of the order of a million individual cells.
N. Jagiella
,
D. Rickert
,
F. J. Theis
,
J. Hasenauer
(Authors)
R. Müller
,
L. Brusch
,
E. Alamoudi
,
J. Hasenauer
(Contributors)
DOI:10.1016/j.cels.2016.12.002
Models
Published Models
Mouse
Hepatocellular Carcinoma
Morpheus Model ID:
M9148
Hepatocyte–sinusoid alignment (HSA) causes asymmetric shapes in early hepatocellular tumors. Introduction The mammalian liver is subdivided into lobes and further into thousands of hexagonal columns, called lobules, which act in parallel.
S. Höhme
,
F. Bertaux
,
W. Weens
,
B. Grasl-Kraupp
,
J. G. Hengstler
,
D. Drasdo
(Authors)
D. Jahn
,
L. Brusch
(Contributors)
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